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生物医学光学与分子影像研究室
 
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 Principal Investigators

Song, Liang(宋亮), PhD, Associate Professor

 

Liang Song received his Ph.D. degree in Biomedical Engineering from Washington University in St. Louis (with Professor Lihong V. Wang) in 2010, his M.Phil. degree in Physics from the Chinese University of Hong Kong in 2006, and his B.Eng. degree in Electronic Science and Technology from Wuhan University in 2003.

He has developed novel photoacoustic microscopy (PAM) capable of imaging optical absorption contrast in vivo with high ultrasonic resolution at large depth in scattering biological tissue. He invented section-illumination PAM and multi-focal optical-resolution PAM, which can potentially speed up the clinical translation of PAM technology for many applications, including early diagnosis of cancer and atherosclerosis, as well as functional imaging of vascular complications in diabetes. He has authored and co-authored more than 30 journal and conference articles (as in 09/2014: h-index: 13; total citations: 458), has four U.S. patents/PCT pending, and has two invited book chapters published. He serves as a regular reviewer for multiple international journals (including Optics Letters, Optics Express, Journal of Biomedical Optics, IEEE UFFC etc.) and is a member of IEEE, OSA, and SPIE.

His current research focuses on developing novel photoacoustic imaging systems and multimodality imaging technologies for the diagnosis and therapy guidance of cancer and cardiovascular atherosclerosis.

 

宋亮获香港中文大学物理学硕士学位、美国华盛顿大学生物医学工程博士学位。研究发展了基于超声阵列的高速,高分辨光声成像技术,实现对较深生物组织的高光学对比、高速、和高超声分辨率的成像,促进了光声成像技术向临床应用转移。20149月,已发表或合作发表期刊和会议论文30余篇(h指数:13;总引用数:458),申请美国和国际发明专利共4项,发表国际著作章节两篇。现为多种国际期刊审稿人(包括Optics Letters, Optics Express, Journal of Biomedical Optics, IEEE UFFC);IEEE,OSA,和SPIE会员。目前研究兴趣包括研究发展新的生物医学光声成像技术,并与其他光学和超声技术结合,为癌症,心血管疾病,和糖尿病的早期诊断和治疗提供有效、低成本的医疗器械。

 

 Tel:86-0755-86392240

Email: liang.song@siat.ac.cn

Address: Room B602, 1068 Xueyuan Boulevard,Xili Nanshan, Shenzhen, 518055,China

 

Zheng, Wei(郑炜), PhD, Associate Professor

 

 

Wei Zheng received his B.S. degree in Optical Engineering from Zhejiang University in 2003, and received his Ph.D. in Electronic and Computer Engineering from Hong Kong University of Science and Technology in 2011 (under the supervision of Professor Jianan Qu). He is currently an associate professor at the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences.

His research has focused on biophotonics field including fluorescence spectroscopy, fluorescence microscopy and nonlinear optical microscopy. At HKUST, he developed a series of novel multi-photon excitation microscopy system to study the feasibility of noninvasive diagnosis of precancer based on the biological autofluorescence. For the first time, he discovered and demonstrated that hemoglobin can emit the Soret autofluorescence via two-photon excitation. His current study is to develop clinical tools that would aid in the understanding and the early diagnosis of various diseases, including cancer and cardiovascular conditions. He has authored and co-authored more than 20 journal and conference articles.

郑炜,2003年毕业于浙江大学电信工程专业,获工学学士学位。 2011年在香港科技大学电子及计算机工程系获博士学位。主要研究方向为生物光子学,荧光多参量显微成像技术及应用,以及非线性光学显微技术及应用等。在博士研究期间,首次发现并证明了血红蛋白在双光子激发下的自发荧光特性,实现了在活体、无损状态下,毛细血管及血液微循环的3D成像。同时,创建了一系列新型、高分辨、多功能的非线性光学显微系统,为活体组织及其细胞的生物特性研究提供有力支撑。在基于自发荧光的早期癌症诊断、心血管疾病研究等方面取得了一系列创新成果。在本领域国际知名期刊上发表SCI收录论文15篇,会议论文8篇。

 

 

  

          Tel:86-0755-86392240   

        Email:zhengwei@siat.ac.cn

 Address: Room B602, 1068 Xueyuan Boulevard,Xili Nanshan, Shenzhen, 518055,China

 Team members 

 
Gong, Xiaojing (龚小竞), PhD, Assistant Professor 

 

Xiao jing GONG is an Assistant Professor at the Shenzhen Institutes of Advanced Technology, Chinese Academy of Science. He received his Ph.D. degree in Fine Instruments and Mechanics from the University of Science and Technology of China in 2007, his B.S. degree in Mechatronics from the Southeast University in 2000.

Dr.GONG joined the IBHE of SIAT in 2007. He focus in the research of Biophotonics, includes Optical Coherence Tomography/Microscopy, Photoacoustic Tomography/Microscopy, Terahertz biomedical imaging, etc. He has authored and co-authored more than 10 journal and conference articles, has 3 Chinese patents and one U.S. patent pending.

龚小竞2000年毕业于东南大学机械电子工程专业,获学士学位;后进入中国科学技术大学,攻读精密仪器与机械专业,于2007年获博士学位。2007年加入深圳先进技术研究院。已发表或合作发表相关论文10余篇,已获批中国专利3项,1项美国专利在审。目前研究方向为:生物光子学研究,包括光学相干层析/显微成像,光声层析/显微成像,太赫兹生物医学影像技术等。 

 

  

Tel: 86-0755-86392242

Email:xj.gong@siat.ac.cn 

 
Liu, Chengbo (刘成波), PhD, Assistant Professor 

 

 

Chengbo Liu received both his Ph.D. (Advisor: Dr. Zhenxi Zhang) and Bachelor degree from Xi’an Jiaotong University, each in 2012 in Biophysics and 2007 in Biomedical Engineering. During his Ph.D. training, he was very grateful to be supported by China Scholarship Council for doing two years visiting research at Duke University, supervised by Dr. Nirmala Ramanujam. His previous research has been mainly focused on tissue spectroscopy and its application in early cancer diagnosis. Now he is an assistant professor at SIAT in Dr. Song lab, working on photoacoustic imaging and translational research. He has authored 4 journal papers so far and besides work, he also enjoys many kinds of sport activities, especially soccer.


刘成波,2007年毕业于西安交通大学生物医学工程专业,获学士学位;2012年获西安交通大学生物物理专业博士学位。攻读博士学位期间获中国国家留学基金委资助赴美国杜克大学进行为期两年的访问研究。博士研究课题为组织光谱技术在肿瘤早期诊断中的应用,已发表科研论文4篇。目前研究方向为光声成像技术及其临床转化研究。 
 

 

  

Tel: 86-0755-86392264

          Email:cb.liu@siat.ac.cn 

 
Zhang, Yang (张洋), PhD, Assistant Professor 

 

 

Yang Zhang received the B.Eng. degree in Biomedical Engineering from the Huazhong University of Science and Technology (HUST), Wuhan, China, in 2009. And he received his Ph.D. in Biomedical Engineering at Wuhan National Laboratory for Optoelectronics, HUST. For the first time, he developed Skull Optical Clearing Solutions (SOCS) which provides an innovative transparent cranial window for visualization of both structural and functional architecture with high spatial- temporal resolution in vivo. 

His research has focused on tissue optics field including: 1. Transport theory of photons in tissue, aim to develop new method for early diagnosis and therapeutic effect evaluation of cancer, 2. Optical clearing technique in vivo, aim to realize the observation and manipulation of neurons, glia and microvasculature in vivo. 

He has authored and co-authored more than 10 journal and conference articles, and 1 Chinese patents.


张洋,2009年毕业于华中科技大学生物医学工程系,获工学学士学位。2014年毕业于华中科技大学武汉光电国家实验室,获工学博士学位。博士期间首次发展了颅骨光透明技术,为实现皮层结构功能的在体成像提供了新方法。 

博士期间主要从事组织光学新技术新方法的研究。具体研究方向包括:1)研究光在不同生物组织中的传输规律,发展疾病诊断与疗效评估的新技术、新方法,2)发展活体组织的光透明技术,实现中枢神经系统、免疫系统、微环境内稳态的实时在体研究。在IEEE Journal of Selected Topics in Quantum Electronics, Laser Physics Letters, Journal of Biomedical Optics等期刊上发表或合作发表SCI收录论文6篇、EI收录论文5篇,已获批中国专利1项。

 

 

Tel: 86-0755-86392264 

Email:zhangyang@siat.ac.cn  

 

 

 

 

 

 

 

 

 

Chen, Jianhua (陈健桦), Assistant Professor  

Jianhua Chen received his Master's degree in Electronic Engineering from Tsinghua University on the topic of ultra-high speed optical fiber transmission and signal processing. His current research focuses on developing data acquisition and imaging schemes for AR/OR-Photoacoustic medical devices.

 

陈健桦2011年获清华大学电子工程系工学硕士学位,研究课题为超高速光纤传输及信号处理系统。目前主要从事用于声学/光学分辨率光声成像医疗器械的数据采集和成像系统的研发工作

 

 

      

 

    Tel: 86-0755-86392264

    Email:jh.chen@siat.ac.cn

 

 
Lin, Riqiang (林日强), Assistant Professor   

Riqiang Lin received his M.E. in  Mechanical Engineering and Automation from Shen Zhen  University in 2011. His research interests are mechanical  designing and mechatronics. His current research focuses  on OR/AR-Photoacoustic Microscopy system design.

 

林日强, 2011年毕业于深圳大学,获工学硕士学位。研究方向为机械设计、机电一体化。 

      

 

        Tel: 86-0755-86392242

     Email:rq.lin@siat.ac.cn 

 

 
Wang, Huina (王慧娜), Research Assistant  
Huina Wang  received her Master's degree in Pharmacology from Wuhan University in June, 2011. Her current research interest includes tumor angiogenesis, cardiovascular atherosclerosis and photoacoustic imaging.

 

 

王慧娜2011年毕业于武汉大学药理学系,获硕士学位,主要研究方向:分子药理、新药研究与评价。目前从事的主要研究方向:光声成像在肿瘤及动脉粥样硬化血管生成中的应用。 

    

       Tel: 86-0755-86392264

        Email:hn.wang@siat.ac.cn

 

 
Yan, Meng (闫盟), Research Assistant   

Meng Yan received her Master's degree in Biomedical engineering from Shenzhen University School of Medicine in 2012.Her current research focuses on applications of high resolution and Super resolution Optical Imaging in biology.

 

闫盟,2012年毕业于深圳大学医学院,获生物医学工程硕士学位。目前的研究方向是超分辨光学成像在生物学上的应用。

        

 

Tel: 86-0755-86392264

       Email:meng.yan@siat.ac.cn

Li, Yan(李岩), Research Assistant  

Yan Li received her Master's degree in Optical Engineering from Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences in 2014. Her current research interest focuses on optical system design for AR/OR-Photoacoustic medical devices.

 

李岩2014年毕业于中国科学院长春光学精密机械与物理研究所,获光学工程学术硕士学位。主要从事声学/光学分辨率光声成像医疗器械光学系统的设计研究工作。  

        

   Tel: 86-0755-86392264

      Email:liyan@siat.ac.cn

Chen, Jingqin (陈敬钦), Research Assistant  

 

 

Jingqin Chen received his Master's degree from South China Normal University in 2014 in Biophysics. During the M.D. training, his research project was “the study of green synthesis of reduced graphene oxide for delivering and photothermally controlling anti-cancer drug release” and he published two papers in Nanoscale Research Letters and Biomaterials respectively, achieving the honor of “the third master's top 10 academic papers”. His previous research has been mainly focused on the synthesis and characterization of nanomaterials and nanomedical imaging probethe study of in vitro and in vivo toxicity of nanomaterials and tumor treatment. 

陈敬钦2014年毕业于华南师范大学生物物理专业,获硕士学位。攻读硕士学位期间,主要研究课题是氧化石墨烯的绿色还原及其传送和光热调控释放抗癌药物的研究,分别在《Nanoscale Research Letters 》和《Biomaterials》发表了一篇文章,并以此获得校第三届硕士十佳学术论文荣誉。目前的主要研究方向是纳米材料和纳米医学成像探针的合成与表征、纳米材料的肿瘤细胞和在体毒性和治疗的研究。

 
 

      

 

   Tel: 86-0755-86392264

   Email:jq.chen@siat.ac.cn

 

 
Li, Mucong (李牧聪), Research Assistant  

Mucong Li received her Master's degree in Control Science and Engineering from Harbin Insititute of Technoloy at Weihai on the topic of ultrasound elasticity imaging in 2014 . Her current research interest focuses on singnal processing of intravascular photoacoustic imaging.

李牧聪2014年毕业于哈尔滨工业大学威海校区,获控制科学与工程专业工学硕士 学位,主要研究内容为超声弹性成像。目前主要从事血管内光声成像的信号处理工作

 

 

      

 

       Tel: 86-0755-86392264

   Email:mc.li@siat.ac.cn

 

 
Zhang, Huajuan (张华娟), Research Assistant  

Huajuan Zhang received her Master’s degree in Chemistry from Fudan University in July, 2012. Her current research focuses on the synthesis and applications of photoacoustic contrast agents and multimodel biomedical contrast agents.

 

张华娟2012年毕业于复旦大学化学系,获分析化学硕士学位。目前的研究方向是光声造影剂的合成和应用,以及多模式生物医学造影剂的合成和应用 

 

 

      

 

    Tel: 86-0755-86392264

   Email:hj.zhang@siat.ac.cn

 

 
Xu, Qiang(许强), Research Assistant  

Qiang Xu received his Master's degree in Optical Engineering from Tianjin University ,key laboratory of opto-electronic information and technical science of Ministry of Education in January 2013.His current research includes Two-photon microscopy system and its application in oncology.

 
许强,2013年1月毕业于天津大学光电信息技术科学教育部重点实验室,获光学工程硕士学位,现主要研究方向是双光子显微系统的相关研究及其在肿瘤学上的应用。

  

     

 

   Tel: 86-0755-86392264

     Email:xu.qiang@siat.ac.cn

Chen, Tingai (陈廷爱), Research Assistant  

Tingai Chen received his Master's degree in Optical Engineering from Beijing Institute of Technology School of Optoelectronics in 2014. His current research interest focuses on Super-resolution structured illumination Microscopy imaging technology.

 

陈廷爱20143月毕业于北京理工大学光电学院,获光学工程硕士学位。目前主要研究方向为超分辨结构光显微成像技术。

 
 

      

 

   Tel: 86-0755-86392264

   Email:ta.chen@siat.ac.cn

 

 
Chen, Longchao (陈龙超), Research Assistant  

Longchao chen received his Master’s degree in Optical Engineering from Fujian Normal University, Ministry of Education Key Laboratory of OptoElectronic Science and Technology for Medicine in 2014. His current interest focuses on designing and researching Laser scanning confocal microscopy and super-resolution microscopy system.

 

陈龙超2014年毕业于福建师范大学医学光电科学与技术教育部重点实验室,获光学工程硕士学位。目前从事激光扫描共聚焦显微镜以及超分辨成像系统的设计和研究工作。 

 

 

      

 

   

   Tel: 86-0755-86392264

   Email:lc.chen@siat.ac.cn

 

 
Zeng, Jing (曾晶), Student  

Jing Zeng comes from Harbin Insititute of Technoloy, whose major is optics. Her current research interest focuses on detection of CTCs by photoacoustic and micro-fluidic chip.

 

曾晶客座学生,光学方向,目前主要从事利用微流控芯片对循环肿瘤细胞光声效应的探测。 

 

 

      

 

   Tel: 86-0755-86392264

   Email:jing.zeng@siat.ac.cn

 

 
Zhang, Yaqi (张亚奇), Student  

Yaqi Zhang, I come from Yunnan University. My major is optics. My research interest focuses on optical system design for AR/OR photoacoustic medical devices.  

张亚奇,云南大学2013级硕士研究生,就读于物理学院光学专业。家乡河南开封,热爱光学成像工作。 

  

 
 

      

 

   Tel: 86-0755-86392264

     Email:zhangyq@siat.ac.cn

 

 
Zeng, Guang (曾光), Student  

Guang Zeng, comes from China Jiliang University, whose major is optical engineering. His current research interest focuses on photoacoustic imaging and translation. 

 

曾光,客座学生,中国计量学院13级硕士研究生,光学工程专业。目前主要从事光声成像系统研究。

 

  

 
 

      

 

  Tel: 86-0755-86392264

  Email:guang.zeng@siat.ac.cn

 

 

 
You, Yujia (游宇佳), Student  

Yujia You, whose major is clinical medicine, comes from the Third Affiliated Hospital of Sun Yat-sen University. Her current research interest focuses on the application of photoacoustic imaging in cancer diagnosis and treatment.

 

 

游宇佳,客座学生,中山大学附属第三医院14级硕士研究生,目前主要研究方向为光声成像在肿瘤诊疗方面的应用。 

  

 
 

      

 

  Tel: 86-0755-86392264

  Email:yj.you@siat.ac.cn